Primary Purpose
| primary_purpose | Study_Count |
|---|---|
| Treatment | 588 |
| Prevention | 112 |
| Diagnostic | 72 |
| Health Services Research | 29 |
| Other | 27 |
| Supportive Care | 23 |
| NA | 17 |
| Basic Science | 11 |
| Screening | 4 |
Craig Mayer, Nick WIlliams, Vojtech Huser
Lister Hill National Center for Biomedical Communications, National Library of Medicine, NIH, Bethesda, MD
See the full regCTG repository at https://github.com/lhncbc/CRI/tree/master/regCTG
To return to the list of conditions and view other reports go to https://lhncbc.github.io/CRI/regCTG/regCTG-condition_report_links.html
| Type | Study_count |
|---|---|
| Total_Studies | 1414 |
| interventional | 883 |
| Observational | 461 |
| Registry | 70 |
```
| intervention_type | Study_Count |
|---|---|
| Drug | 241 |
| Device | 120 |
| Procedure | 106 |
| Drug|placebo | 99 |
| Other | 87 |
| Behavioral | 62 |
| Drug|Procedure | 21 |
| Biological | 20 |
| Diagnostic Test | 16 |
| Biological|placebo | 14 |
| Device|Other | 9 |
| Drug|Other | 9 |
| Device|Drug | 8 |
| Device|Procedure | 8 |
| Other|Procedure | 7 |
| Behavioral|Other | 6 |
| Behavioral|Drug | 4 |
| Genetic | 4 |
| Device|Drug|Procedure | 3 |
| Dietary Supplement | 3 |
| Drug|placebo|Procedure | 3 |
| Biological|Other | 2 |
| Biological|Procedure | 2 |
| Device|Drug|placebo | 2 |
| Dietary Supplement|placebo | 2 |
| Drug|Genetic | 2 |
| Drug|Other|placebo | 2 |
| Drug|Other|Procedure | 2 |
| Other|placebo | 2 |
| Behavioral|Biological | 1 |
| Behavioral|Device | 1 |
| Behavioral|Diagnostic Test | 1 |
| Behavioral|Procedure | 1 |
| Biological|Device|Other|Procedure | 1 |
| Biological|Device|placebo | 1 |
| Biological|Drug | 1 |
| Biological|Drug|Procedure | 1 |
| Combination Product | 1 |
| Combination Product|Procedure | 1 |
| Device|Drug|Other | 1 |
| Diagnostic Test|Other | 1 |
| Dietary Supplement|Drug | 1 |
| Drug|Procedure|Radiation | 1 |
| placebo | 1 |
| Procedure|Radiation | 1 |
| Radiation | 1 |
| Country | Study_Count |
|---|---|
| United States | 134 |
| NA | 75 |
| Canada | 52 |
| Italy | 44 |
| China | 42 |
| France | 39 |
| Germany | 37 |
| Korea, Republic of | 34 |
| Denmark | 33 |
| United Kingdom | 28 |
| Netherlands | 25 |
| Sweden | 23 |
| Norway | 22 |
| Spain | 20 |
| Brazil | 18 |
| Japan | 14 |
| Switzerland | 14 |
| Greece | 13 |
| Poland | 9 |
| Russian Federation | 8 |
| Iran, Islamic Republic of | 7 |
| Turkey | 7 |
| Austria | 6 |
| Israel | 6 |
| Taiwan | 6 |
| United States|Canada | 6 |
| Belgium | 5 |
| Finland | 4 |
| India | 4 |
| Singapore | 4 |
| Czech Republic | 3 |
| Czechia | 3 |
| Indonesia | 3 |
| Pakistan | 3 |
| Portugal | 3 |
| Slovenia | 3 |
| Austria|Germany | 2 |
| Croatia | 2 |
| Denmark|Iceland|Sweden | 2 |
| Egypt | 2 |
| France|Germany | 2 |
| Italy|Switzerland | 2 |
| Kazakhstan | 2 |
| Netherlands|Poland | 2 |
| Romania | 2 |
| Thailand | 2 |
| United States|Puerto Rico | 2 |
| Algeria|Australia|Austria|Canada|Denmark|France|Germany|Hungary|Italy|Netherlands|Spain|Sweden|United Kingdom | 1 |
| Argentina | 1 |
| Argentina|Australia|Brazil|Canada|China|Colombia|New Zealand|Peru|Russian Federation|Ukraine | 1 |
| Argentina|Brazil|Italy|Paraguay|Spain | 1 |
| Argentina|Canada|India | 1 |
| Australia | 1 |
| Australia|Bangladesh|Czechia|Denmark|Latvia|Norway|Sweden|United Kingdom | 1 |
| Australia|Canada|Chile|France|Mexico|Romania|Russian Federation|Serbia|Spain | 1 |
| Austria|Belgium|Brazil|Canada|Chile|France|Germany|Greece|Italy|Norway|Peru|Poland|Russian Federation|Serbia|Spain|United Kingdom | 1 |
| Austria|Belgium|Canada|Czech Republic|Finland|France|Germany|Hungary|Israel|Italy|Latvia|Lithuania|Netherlands|Poland|Portugal|Romania|Slovakia|Sweden|Turkey | 1 |
| Austria|Belgium|Czech Republic|Denmark|Germany|Lithuania|Netherlands|Poland|Romania|Sweden|Switzerland | 1 |
| Austria|Belgium|Hungary|Netherlands|Poland | 1 |
| Austria|Denmark|Slovenia|Sweden | 1 |
| Austria|Estonia|Hungary|Poland|Serbia|Slovenia|Sweden|United Kingdom | 1 |
| Austria|Germany|Hungary|Poland|United Kingdom | 1 |
| Austria|Germany|Italy | 1 |
| Austria|Germany|Switzerland | 1 |
| Belgium|Czechia|Luxembourg|Netherlands | 1 |
| Belgium|Finland|Netherlands|Switzerland|United Kingdom | 1 |
| Belgium|France | 1 |
| Belgium|France|Spain | 1 |
| Belgium|Germany|Netherlands | 1 |
| Belgium|Hungary|Poland | 1 |
| Belgium|Italy|Netherlands | 1 |
| Belgium|Switzerland | 1 |
| Belgium|United States|Argentina|Austria|Bulgaria|Canada|Czech Republic|Denmark|France|Germany|Israel|Netherlands|Poland|Romania|South Africa|Spain|Sweden|Switzerland|United Kingdom | 1 |
| Brazil|Czechia|Hungary|Israel|Netherlands|Poland|Russian Federation|Slovakia|Spain|United Kingdom | 1 |
| Brazil|Italy|Macedonia, The Former Yugoslav Republic of|Serbia|Spain | 1 |
| Bulgaria|United States|Argentina|Australia|Canada|Czechia|Denmark|France|Germany|Hungary|Italy|Korea, Republic of|Netherlands|Poland|Russian Federation|Spain|Sweden|Taiwan|United Kingdom | 1 |
| Canada|Chile|Spain | 1 |
| Canada|Croatia|Czech Republic|Germany|Hungary|India|Israel|Lebanon|Poland|Romania|Russian Federation|Slovakia|Slovenia|South Africa|Spain|Turkey|United Kingdom | 1 |
| Canada|Czech Republic|France|Germany|Greece|Hungary|Netherlands|Poland|Slovakia|Spain|United Kingdom | 1 |
| Canada|France | 1 |
| Canada|United States|Bangladesh|India|Iran, Islamic Republic of|Pakistan|Tunisia | 1 |
| Canada|United States|Netherlands|Poland | 1 |
| China|Hong Kong|Korea, Republic of | 1 |
| China|United Kingdom | 1 |
| Czechia|France|Germany|Hungary|Italy|Poland|Spain | 1 |
| Czechia|Germany|Hungary|Netherlands|Norway|Poland|Singapore|Sweden | 1 |
| Czechia|Germany|Israel|Italy|Spain | 1 |
| Czechia|Slovakia | 1 |
| Denmark|France|Germany|Netherlands | 1 |
| Denmark|France|Norway|Sweden | 1 |
| Denmark|Germany | 1 |
| Denmark|Netherlands|Spain|Switzerland | 1 |
| Denmark|Norway | 1 |
| Denmark|Spain | 1 |
| Denmark|Switzerland|United Kingdom | 1 |
| France|Italy|Poland | 1 |
| France|Spain | 1 |
| France|Switzerland | 1 |
| France|United Kingdom | 1 |
| Germany|Austria | 1 |
| Germany|Italy | 1 |
| Germany|Switzerland | 1 |
| Germany|United Kingdom | 1 |
| Germany|United States|Australia|Canada|Israel|Italy|Puerto Rico|United Kingdom | 1 |
| Greece|Hungary|India|Netherlands|Spain|Sweden|Thailand|Tunisia|Turkey|Ukraine|Germany|United States|Argentina|Australia|Belgium|Brazil|Bulgaria|Canada|Chile|China|Colombia|Croatia|Czech Republic|Denmark|Egypt|France|Israel|Japan|Korea, Republic of|Latvia|Lithuania|Malaysia|Mexico|Morocco|New Zealand|Philippines|Poland|Portugal|Romania|Russian Federation|Serbia|Slovakia|United Kingdom | 1 |
| Greece|United States|China|Argentina|Australia|Austria|Belgium|Brazil|Bulgaria|Canada|Colombia|Croatia|Czechia|Denmark|Finland|France|Germany|Hungary|India|Israel|Italy|Korea, Republic of|Mexico|Netherlands|Norway|Peru|Philippines|Poland|Portugal|Romania|Russian Federation|Singapore|Slovakia|South Africa|Spain|Sweden|Switzerland|Taiwan|Thailand|Turkey|United Kingdom | 1 |
| Ireland | 1 |
| Ireland|Netherlands | 1 |
| Italy|Netherlands | 1 |
| Italy|Netherlands|Spain | 1 |
| Italy|Poland|Spain | 1 |
| Italy|Spain | 1 |
| Japan|Poland|Portugal|Ukraine|United States|Argentina|Australia|Brazil|Bulgaria|Canada|China|Czechia|Denmark|Estonia|France|Germany|Greece|Hungary|Korea, Republic of|Latvia|Lithuania|Malaysia|Mexico|Netherlands|Romania|Russian Federation|Slovakia|South Africa|Spain|Sweden|Turkey|United Kingdom | 1 |
| Mauritius | 1 |
| Netherlands|Norway|Poland|Switzerland | 1 |
| Netherlands|Spain | 1 |
| New Zealand|Norway|Poland|United States|Australia|Belgium|Canada|Czech Republic|Denmark|Finland|Germany|Hungary|Israel|Italy|Netherlands|Portugal|Spain|Sweden | 1 |
| Palestinian Territory, occupied | 1 |
| Poland|South Africa | 1 |
| Portugal|Spain | 1 |
| South Africa | 1 |
| Switzerland|Austria|Belgium|Czechia|Germany|Israel|Poland | 1 |
| United States|Argentina | 1 |
| United States|Argentina|Australia|Austria|Belarus|Belgium|Brazil|Bulgaria|Canada|Chile|China|Croatia|Denmark|Estonia|Finland|France|Germany|Greece|Hong Kong|Hungary|India|Ireland|Israel|Italy|Jordan|Korea, Republic of|Latvia|Lebanon|Lithuania|Malaysia|Mexico|Netherlands|Norway|Poland|Portugal|Romania|Russian Federation|Singapore|Slovakia|South Africa|Spain|Sweden|Switzerland|Thailand|Turkey|Ukraine|United Kingdom|Uruguay | 1 |
| United States|Argentina|Australia|Austria|Belarus|Belgium|Brazil|Bulgaria|Canada|Chile|Colombia|Croatia|Czech Republic|Egypt|Estonia|France|Germany|Greece|Hong Kong|Hungary|India|Indonesia|Israel|Italy|Jordan|Korea, Republic of|Latvia|Lebanon|Lithuania|Macedonia, The Former Yugoslav Republic of|Malaysia|Mexico|Montenegro|Netherlands|New Zealand|Norway|Panama|Peru|Poland|Portugal|Romania|Russian Federation|Serbia|Singapore|Slovakia|South Africa|Spain|Switzerland|Taiwan|Thailand|Tunisia|Turkey|Ukraine|United Kingdom|Vietnam | 1 |
| United States|Argentina|Australia|Austria|Belgium|Brazil|Canada|France|Germany|Hungary|Ireland|Israel|Italy|Mexico|Netherlands|Poland|Portugal|Puerto Rico|Russian Federation|South Africa|Spain|Sweden|Turkey|United Kingdom | 1 |
| United States|Argentina|Australia|Belgium|Brazil|Bulgaria|Canada|Chile|China|Colombia|Czech Republic|France|Germany|Hungary|Italy|Japan|Korea, Republic of|Netherlands|Norway|Peru|Philippines|Poland|Romania|Russian Federation|Slovakia|South Africa|Spain|Sweden|Turkey|Ukraine|United Kingdom | 1 |
| United States|Argentina|Australia|Belgium|Brazil|Canada|Chile|Czech Republic|France|India|Korea, Republic of|Mexico|Netherlands|Poland|Portugal|Russian Federation|Spain|Turkey | 1 |
| United States|Argentina|Belgium|Canada|Colombia|Czech Republic|Denmark|Germany|Hungary|India|Israel|Italy|Korea, Republic of|Netherlands|Norway|Poland|Russian Federation|Slovakia|Spain|Sweden|Turkey|United Kingdom|Venezuela | 1 |
| United States|Australia|Austria|Belgium|Brazil|Canada|China|Czech Republic|Finland|France|Germany|Greece|Hungary|Korea, Republic of|Macedonia, The Former Yugoslav Republic of|Netherlands|New Zealand|Serbia|Spain|United Kingdom | 1 |
| United States|Australia|Austria|Belgium|Canada|Czech Republic|Denmark|France|Germany|Italy|Netherlands|New Zealand|Poland|Portugal|Spain|Sweden|Switzerland | 1 |
| United States|Australia|Austria|Belgium|Czechia|Denmark|France|Germany|Hungary|Latvia|Netherlands|Poland|Slovakia|Spain | 1 |
| United States|Australia|Austria|Bulgaria|Canada|Czech Republic|Denmark|France|Germany|Hungary|Israel|Italy|Netherlands|Poland|Spain|United Kingdom | 1 |
| United States|Australia|Belgium|Canada|France|Germany|Israel|Poland|Spain | 1 |
| United States|Australia|Belgium|Denmark|France|Germany|Italy|Netherlands|New Zealand|Portugal|Spain|United Kingdom | 1 |
| United States|Australia|Belgium|France|Germany|India|Ireland|Italy|Netherlands|United Kingdom | 1 |
| United States|Australia|Canada|Germany|India|Netherlands|Poland|Spain|United Kingdom | 1 |
| United States|Australia|Czechia|Germany|Hungary|Latvia|Malaysia|New Zealand|Poland|Russian Federation|Singapore|Slovakia|Switzerland | 1 |
| United States|Austria|Germany|Netherlands|Poland|United Kingdom | 1 |
| United States|Belgium|Canada|Finland|France|Germany|Hungary|Italy|Norway|Saudi Arabia|Slovakia|South Africa|Spain|Sweden|United Kingdom | 1 |
| United States|Brazil|Canada | 1 |
| United States|Canada|Poland | 1 |
| United States|Canada|Puerto Rico | 1 |
| United States|Denmark|France|Germany|Hungary|Saudi Arabia|Slovakia | 1 |
| United States|France|Germany|United Kingdom | 1 |
| United States|Germany|Hungary|Israel|Netherlands | 1 |
| United States|Germany|Poland | 1 |
| United States|Greece|India | 1 |
| United States|Hungary|Poland|United Kingdom | 1 |
| United States|Israel | 1 |
| United States|Poland | 1 |
| Site_count | Study_Count |
|---|---|
| 1 | 598 |
| 2 | 64 |
| 3 | 26 |
| 4 | 20 |
| 5 | 22 |
| 6 | 11 |
| 7 | 8 |
| 8 | 8 |
| 9 | 2 |
| 10 | 5 |
| 11 | 6 |
| 12 | 7 |
| 13 | 7 |
| 14 | 5 |
| 15 | 2 |
| 16 | 6 |
| 17 | 5 |
| 18 | 2 |
| 19 | 1 |
| 20 | 2 |
| 21 | 1 |
| 23 | 2 |
| 24 | 4 |
| 25 | 3 |
| 26 | 2 |
| 28 | 1 |
| 29 | 3 |
| 30 | 1 |
| 31 | 3 |
| 32 | 2 |
| 33 | 1 |
| 34 | 1 |
| 38 | 2 |
| 39 | 1 |
| 40 | 1 |
| 41 | 2 |
| 45 | 1 |
| 47 | 2 |
| 48 | 3 |
| 52 | 2 |
| 55 | 1 |
| 58 | 1 |
| 64 | 1 |
| 65 | 1 |
| 66 | 1 |
| 69 | 1 |
| 71 | 1 |
| 74 | 1 |
| 75 | 1 |
| 81 | 1 |
| 82 | 1 |
| 85 | 1 |
| 86 | 1 |
| 87 | 1 |
| 91 | 1 |
| 94 | 1 |
| 95 | 1 |
| 101 | 1 |
| 102 | 1 |
| 108 | 1 |
| 113 | 1 |
| 115 | 1 |
| 127 | 1 |
| 153 | 2 |
| 183 | 1 |
| 189 | 1 |
| 190 | 1 |
| 201 | 1 |
| 235 | 1 |
| 272 | 1 |
| 349 | 1 |
| 471 | 1 |
| 489 | 1 |
| 578 | 1 |
| 584 | 1 |
| 607 | 1 |
| 847 | 1 |
| Phase | Study_Count |
|---|---|
| N/A | 348 |
| Phase 4 | 201 |
| Phase 3 | 151 |
| Phase 2 | 100 |
| Phase 2/Phase 3 | 32 |
| Phase 1 | 27 |
| Phase 1/Phase 2 | 21 |
| Early Phase 1 | 3 |
| Number_of_Arms | Count_of_Studies |
|---|---|
| 1 | 85 |
| 2 | 561 |
| 3 | 93 |
| 4 | 38 |
| 5 | 5 |
| 6 | 4 |
| NA | 97 |
| Count of Versions | Count of Studies |
|---|---|
| 1 | 93 |
| 2 | 130 |
| 3 | 135 |
| 4 | 116 |
| 5 | 91 |
| 6 | 71 |
| 7 | 53 |
| 8 | 44 |
| 9 | 34 |
| 10 | 18 |
| 11 | 14 |
| 12 | 12 |
| 13 | 7 |
| 14 | 5 |
| 15 | 5 |
| 16 | 3 |
| 17 | 4 |
| 18 | 8 |
| 19 | 3 |
| 20 | 1 |
| 21 | 1 |
| 22 | 4 |
| 24 | 1 |
| 25 | 1 |
| 26 | 6 |
| 29 | 1 |
| 31 | 1 |
| 34 | 1 |
| 36 | 2 |
| 37 | 2 |
| 40 | 1 |
| 42 | 1 |
| 44 | 2 |
| 45 | 2 |
| 47 | 1 |
| 48 | 2 |
| 58 | 1 |
| 67 | 2 |
| 72 | 1 |
| 76 | 1 |
| 79 | 1 |
| 84 | 1 |
| Change Type | Count_of_Changes | Count_of_Studies | ratio |
|---|---|---|---|
| Study Status | 4730 | 790 | 5.987342 |
| Contacts/Locations | 2404 | 668 | 3.598802 |
| Recruitment Status | 1165 | 686 | 1.698251 |
| Study Design | 885 | 570 | 1.552632 |
| None (earliest Version on record) | 883 | 883 | 1.000000 |
| Outcome Measures | 690 | 401 | 1.720698 |
| Sponsor/Collaborators | 529 | 337 | 1.569733 |
| Arms | 492 | 336 | 1.464286 |
| Interventions | 492 | 336 | 1.464286 |
| Eligibility | 489 | 329 | 1.486322 |
| Study Identification | 473 | 287 | 1.648084 |
| Study Description | 455 | 312 | 1.458333 |
| Oversight | 347 | 277 | 1.252708 |
| References | 237 | 164 | 1.445122 |
| Conditions | 160 | 128 | 1.250000 |
| More Information | 127 | 41 | 3.097561 |
| Results | 85 | 85 | 1.000000 |
| IPDSharing | 74 | 71 | 1.042253 |
| Results Submission Events | 30 | 30 | 1.000000 |
| Baseline Characteristics | 25 | 23 | 1.086957 |
| Documents | 20 | 18 | 1.111111 |
| Reported Adverse Events | 17 | 16 | 1.062500 |
| Participant Flow | 14 | 12 | 1.166667 |
| Measure | Early.Phase.1 | N.A | Phase.1 | Phase.1.Phase.2 | Phase.2 | Phase.2.Phase.3 | Phase.3 | Phase.4 |
|---|---|---|---|---|---|---|---|---|
| Min. | 30.0000 | 2.000 | 6.0000 | 10.00 | 8.0000 | 20.0000 | 10.000 | 11.000 |
| 1st Qu. | 95.0000 | 60.000 | 15.0000 | 13.75 | 50.0000 | 89.7500 | 120.000 | 80.000 |
| Median | 160.0000 | 142.000 | 27.0000 | 22.00 | 105.0000 | 110.5000 | 392.000 | 165.000 |
| Mean | 126.6667 | 1345.139 | 139.2593 | 54.50 | 201.2929 | 157.4375 | 2709.152 | 1077.265 |
| 3rd Qu. | 175.0000 | 549.750 | 34.0000 | 92.50 | 221.5000 | 242.5000 | 2305.000 | 606.000 |
| Max. | 190.0000 | 50000.000 | 2800.0000 | 200.00 | 1267.0000 | 380.0000 | 39876.000 | 46000.000 |
| group_type | Group_Count |
|---|---|
| Experimental | 677 |
| Active Comparator | 542 |
| Placebo Comparator | 190 |
| No Intervention | 144 |
| Other | 114 |
| NA | 97 |
| Sham Comparator | 20 |
| intervention_model | Study_Count |
|---|---|
| Parallel Assignment | 683 |
| Single Group Assignment | 115 |
| NA | 29 |
| Crossover Assignment | 27 |
| Factorial Assignment | 23 |
| Sequential Assignment | 6 |
| primary_purpose | Study_Count |
|---|---|
| Treatment | 588 |
| Prevention | 112 |
| Diagnostic | 72 |
| Health Services Research | 29 |
| Other | 27 |
| Supportive Care | 23 |
| NA | 17 |
| Basic Science | 11 |
| Screening | 4 |
| Country | Study_Count |
|---|---|
| NA | 115 |
| United States | 74 |
| United Kingdom | 31 |
| China | 30 |
| Germany | 20 |
| France | 18 |
| Italy | 15 |
| Sweden | 12 |
| Canada | 11 |
| Austria | 8 |
| Israel | 8 |
| Korea, Republic of | 8 |
| Norway | 8 |
| Netherlands | 7 |
| Turkey | 7 |
| Denmark | 6 |
| Greece | 6 |
| Romania | 6 |
| Poland | 5 |
| Spain | 5 |
| Belgium | 4 |
| Brazil | 4 |
| Russian Federation | 4 |
| Switzerland | 4 |
| Taiwan | 4 |
| United States|Canada | 3 |
| Finland | 2 |
| Japan | 2 |
| Singapore | 2 |
| Argentina|Belgium|Brazil|Denmark|Finland|France|Germany|Greece|Italy|Luxembourg|Mexico|Netherlands|Norway|Poland|Romania|Slovenia|Spain|Turkey|United Kingdom|Venezuela | 1 |
| Argentina|Norway | 1 |
| Australia | 1 |
| Bangladesh|Brunei Darussalam|China|Egypt|India|Indonesia|Korea, Republic of|Malaysia|Pakistan|Philippines|Saudi Arabia|Singapore|South Africa|Taiwan|Thailand|Tunisia | 1 |
| Belgium|Bulgaria|Croatia|Czechia|Denmark|Finland|Germany|Greece|Hungary|Netherlands|Poland|Slovakia|Spain|Sweden|Switzerland|United Kingdom | 1 |
| Belgium|France | 1 |
| Brazil|Canada|China|Colombia|India|Malaysia|Spain | 1 |
| Brazil|Germany|Italy|United Kingdom | 1 |
| Bulgaria | 1 |
| Canada|Netherlands | 1 |
| China|India|Korea, Republic of|Singapore | 1 |
| Colombia | 1 |
| Costa Rica | 1 |
| Czech Republic | 1 |
| Czechia|Estonia|Germany|Hungary|Lithuania|Poland|Serbia|United Kingdom | 1 |
| Czechia|Italy|Poland|Spain|Switzerland | 1 |
| Egypt | 1 |
| Finland|Germany | 1 |
| Finland|Germany|Italy|Poland|Slovenia|Spain|Sweden | 1 |
| Haiti | 1 |
| Indonesia | 1 |
| Iran, Islamic Republic of | 1 |
| Japan|Korea, Republic of|Spain | 1 |
| Jordan | 1 |
| Pakistan | 1 |
| Poland|Slovenia | 1 |
| Saudi Arabia | 1 |
| Serbia | 1 |
| Spain|Sweden | 1 |
| Sweden|United Kingdom | 1 |
| United States|Australia|Brazil|Canada|China|Hong Kong|Italy|Malaysia|Poland|Russian Federation|Spain|United Kingdom | 1 |
| United States|Israel | 1 |
| Site_count | Study_Count |
|---|---|
| 1 | 376 |
| 2 | 27 |
| 3 | 7 |
| 4 | 8 |
| 5 | 7 |
| 6 | 1 |
| 7 | 2 |
| 8 | 4 |
| 10 | 2 |
| 11 | 2 |
| 13 | 2 |
| 15 | 1 |
| 17 | 2 |
| 18 | 2 |
| 19 | 1 |
| 20 | 1 |
| 22 | 2 |
| 23 | 1 |
| 24 | 2 |
| 29 | 1 |
| 42 | 1 |
| 49 | 1 |
| 52 | 1 |
| 56 | 1 |
| 68 | 1 |
| 81 | 1 |
| 92 | 1 |
| 93 | 1 |
| 144 | 1 |
| 411 | 1 |
| Count of Versions | Count of Studies |
|---|---|
| 1 | 73 |
| 2 | 117 |
| 3 | 94 |
| 4 | 69 |
| 5 | 37 |
| 6 | 9 |
| 7 | 16 |
| 8 | 9 |
| 9 | 9 |
| 11 | 2 |
| 12 | 5 |
| 13 | 5 |
| 14 | 2 |
| 15 | 2 |
| 16 | 1 |
| 17 | 1 |
| 18 | 2 |
| 19 | 1 |
| 20 | 1 |
| 21 | 1 |
| 23 | 1 |
| 29 | 1 |
| 32 | 1 |
| 36 | 1 |
| 37 | 1 |
| Change Type | Count_of_Changes | Count_of_Studies | ratio |
|---|---|---|---|
| Study Status | 1395 | 388 | 3.595361 |
| Contacts/Locations | 504 | 231 | 2.181818 |
| None (earliest Version on record) | 461 | 461 | 1.000000 |
| Recruitment Status | 362 | 253 | 1.430830 |
| Study Design | 312 | 233 | 1.339056 |
| Study Identification | 196 | 136 | 1.441177 |
| Sponsor/Collaborators | 187 | 144 | 1.298611 |
| Study Description | 163 | 124 | 1.314516 |
| Eligibility | 160 | 131 | 1.221374 |
| Outcome Measures | 139 | 97 | 1.432990 |
| References | 106 | 52 | 2.038461 |
| Oversight | 82 | 79 | 1.037975 |
| Groups | 63 | 58 | 1.086207 |
| Interventions | 63 | 58 | 1.086207 |
| Conditions | 45 | 41 | 1.097561 |
| IPDSharing | 27 | 27 | 1.000000 |
| More Information | 17 | 8 | 2.125000 |
| Results | 15 | 15 | 1.000000 |
| Baseline Characteristics | 8 | 7 | 1.142857 |
| Reported Adverse Events | 7 | 5 | 1.400000 |
| Results Submission Events | 4 | 4 | 1.000000 |
| Participant Flow | 3 | 3 | 1.000000 |
| Documents | 2 | 2 | 1.000000 |
| Measure | Observational |
|---|---|
| Min | 0.00 |
| 1st Qu | 122.50 |
| Median | 555.00 |
| Mean | 35508.49 |
| 3rd Qu | 2981.25 |
| Max | 2240000.00 |
| observational_model | Study_Count |
|---|---|
| Cohort | 269 |
| NA | 79 |
| Case-Only | 36 |
| Case Control | 31 |
| Case-Control | 24 |
| Other | 14 |
| Defined Population, Natural History | 3 |
| Ecologic or Community | 2 |
| Case-Crossover | 1 |
| Defined Population | 1 |
| Family-Based | 1 |
| time_perspective | Study_Count |
|---|---|
| Prospective | 286 |
| Retrospective | 87 |
| NA | 56 |
| Cross-Sectional | 17 |
| Other | 11 |
| Longitudinal, Prospective | 3 |
| Cross-Sectional, Prospective | 1 |
| Country | Study_Count |
|---|---|
| NA | 14 |
| United States | 9 |
| Germany | 6 |
| United Kingdom | 6 |
| Korea, Republic of | 5 |
| China | 4 |
| Brazil | 3 |
| Denmark | 2 |
| Egypt | 2 |
| France | 2 |
| Hungary | 2 |
| Italy | 2 |
| Netherlands | 2 |
| Sweden | 2 |
| Belgium|Netherlands | 1 |
| Colombia | 1 |
| Greece | 1 |
| Hong Kong|Korea, Republic of|Singapore|Taiwan|Thailand | 1 |
| Mexico | 1 |
| Russian Federation | 1 |
| Spain | 1 |
| Tunisia | 1 |
| Turkey | 1 |
| Site_count | Study_Count |
|---|---|
| 1 | 53 |
| 2 | 2 |
| 3 | 2 |
| 4 | 2 |
| 5 | 1 |
| 9 | 2 |
| 10 | 1 |
| 14 | 2 |
| 16 | 2 |
| 37 | 1 |
| 55 | 1 |
| 90 | 1 |
| Count of Versions | Count of Studies |
|---|---|
| 1 | 18 |
| 2 | 10 |
| 3 | 17 |
| 4 | 7 |
| 5 | 3 |
| 6 | 3 |
| 7 | 5 |
| 8 | 1 |
| 9 | 2 |
| 11 | 2 |
| 28 | 1 |
| 59 | 1 |
| Change Type | Count_of_Changes | Count_of_Studies | ratio |
|---|---|---|---|
| Study Status | 249 | 52 | 4.788462 |
| Contacts/Locations | 111 | 33 | 3.363636 |
| None (earliest Version on record) | 70 | 70 | 1.000000 |
| Recruitment Status | 44 | 31 | 1.419355 |
| Study Description | 43 | 19 | 2.263158 |
| Study Design | 29 | 26 | 1.115385 |
| Outcome Measures | 22 | 15 | 1.466667 |
| Eligibility | 17 | 13 | 1.307692 |
| Study Identification | 14 | 9 | 1.555556 |
| References | 13 | 9 | 1.444444 |
| Groups | 12 | 9 | 1.333333 |
| Interventions | 12 | 9 | 1.333333 |
| Sponsor/Collaborators | 9 | 8 | 1.125000 |
| IPDSharing | 6 | 6 | 1.000000 |
| Oversight | 6 | 6 | 1.000000 |
| Conditions | 5 | 5 | 1.000000 |
| Documents | 3 | 3 | 1.000000 |
| More Information | 1 | 1 | 1.000000 |
| Results | 1 | 1 | 1.000000 |
| Results Submission Events | 1 | 1 | 1.000000 |
| Measure | Registries |
|---|---|
| Min | 11.00 |
| 1st Qu | 533.00 |
| Median | 2000.00 |
| Mean | 73388.97 |
| 3rd Qu | 7425.00 |
| Max | 2240000.00 |
| observational_model | Study_Count |
|---|---|
| Cohort | 52 |
| Case-Control | 7 |
| Case-Only | 6 |
| Other | 3 |
| Ecologic or Community | 1 |
| NA | 1 |
| time_perspective | Study_Count |
|---|---|
| Prospective | 60 |
| Other | 4 |
| Cross-Sectional | 3 |
| NA | 3 |
| target_duration | Study_Count |
|---|---|
| 1 Year | 10 |
| 12 Months | 9 |
| 5 Years | 8 |
| 10 Years | 7 |
| 2 Years | 7 |
| 3 Years | 5 |
| 6 Months | 3 |
| 1 Day | 2 |
| 1 Month | 2 |
| 30 Days | 2 |
| 1 Week | 1 |
| 105 Months | 1 |
| 13 Months | 1 |
| 13 Years | 1 |
| 15 Years | 1 |
| 180 Days | 1 |
| 24 Months | 1 |
| 28 Days | 1 |
| 4 Years | 1 |
| 40 Days | 1 |
| 5 Days | 1 |
| 6 Years | 1 |
| 7 Years | 1 |
| 8 Years | 1 |
| 88 Months | 1 |